Hemofili A, alvorlig grad
Engelsk navn: Severe hemophilia A
Engelske synonym: Severe congenital F8 deficiency,Severe congenital factor VIII deficiency
A severe form of hemophilia A characterized by a large deficiency of factor VIII (biological activity <1 IU/dL) leading to frequent spontaneous hemorrhage and abnormal bleeding as a result of minor injuries, or following trauma, surgery or tooth extraction. It primarily affects males but may also be observed in female carriers of disease-causing mutations.
Klassifiseringsnivå: Subtype of disorder